• July 22, 2022

Keto Versus Mediterranean Weight-reduction plan: Which Is Greatest for T2 Diabetics and Prediabetics?

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Impact of a Ketogenic Weight-reduction plan versus a Mediterranean Weight-reduction plan on HbA1c in People with Prediabetes and Sort 2 Diabetes Mellitus: the Interventional Keto-Med Randomized Crossover Trial

Proper off the bat, I do not like that they studied each diabetes and prediabetics. There have been solely 40 unique examine members, with full information on solely 33. Why lump the 2 collectively?

Members adopted every weight loss program for 12 weeks then lab information and physique weight had been assessed.

The researchers conclusions:

HbA1c [a measure of blood sugar control] was not completely different between weight loss program phases after 12-weeks, however improved from baseline on each diets, probably attributable to a number of shared dietary facets. WFKD [ketogenic diet] was useful for higher lower in triglycerides, but in addition had potential untoward dangers from elevated LDL-C, and decrease nutrient intakes from avoiding legumes, fruits, and entire intact grains, in addition to being much less sustainable.

Triglycerides dropped extra on the keto weight loss program, no shock. Physique weight dropped the identical for each diets, 7-8%. HDL-cholesterol (the “good ldl cholesterol”) rose 11% on keto and seven% on the Mediterranean weight loss program. HgbA1c dropped the identical on each diets, about 8% from baseline. Each diets result in consuming ~300 energy much less per day than baseline consumption.

Dr Bret Scher addressed the elevated LDL-cholesterol (aka “dangerous ldl cholesterol”) over at DietDoctor.com:

The authors reported that LDL “dangerously” rose 10% on the keto weight loss program. However was it actually a harmful change? Triglycerides went down on the keto weight loss program, as we might count on. And as we noticed in 2018 with the Virta Well being trial, on common, LDL went up 10%. Nonetheless, the calculated cardiac danger rating went down 12%.

By way of answering the headline query, Keto Versus Mediterranean Weight-reduction plan: Which Is Greatest for T2 Diabetics and Prediabetics?, the reply actually relies on long-term information regarding longevity and varied ailments. This examine would not reply the query.

What say you?

Steve Parker, MD

front cover of Conquer Diabetes and Prediabetes